https://wiki.chemika.be/api.php?action=feedcontributions&feedformat=atom&user=Jakobroose 2026-07-28T12:49:37Z Gebruikersbijdragen MediaWiki 1.43.0 https://wiki.chemika.be/index.php?title=Biomolecular_Modelling&diff=1987 2020-01-22T11:34:17Z

<p>Jakobroose: /* Examenvragen */</p> <hr /> <div>[[Categorie: Mabb]]<br /> <br /> == Vakinformatie ==<br /> Biomolecular modelling<br /> <br /> ECTS-fiche: https://onderwijsaanbod.kuleuven.be/syllabi/e/G0G79AE.htm<br /> <br /> == Examenvragen ==<br /> '''Exam of 21/01/2020'''<br /> <br /> 1. Describe the different methods for structure prediction and explain in which situation they are used.<br /> <br /> 2. Differences and similarities between genetic algorithms and monte carlo simulated annealing. <br /> <br /> 3. You have a set of molecules able to bind a target, but they can not be used as drugs. There is a database of drug-like compounds. You have the structure of the active ligands, of the target but not of the complex. What would you do to find new drugs<br /> <br /> 4. Rndom question: describe the steps of moelcular dynamics <br /> <br /> 5. True or false questions: <br /> a. The PDB is the best format to store data of protein-ligand complexes <br /> b. FF for small molecules can not be used for proteins<br /> c. The first step of conjugate gradient is steepest descent<br /> <br /> '''Exam of 20/01/2020'''<br /> <br /> 1. (Oral) Describe Monte Carlo simulation and what it is used for.<br /> <br /> 2. (Oral)Random question: explain the enrichment factor . <br /> <br /> 3. What is a scoring function and which types are there?<br /> <br /> 4. You have a set of molecules able to bind a target, but they can not be used as drugs. There is a database of drug-like compounds. You have the structure of the active ligands, of the target but not of the complex. What would you do to find new drugs<br /> <br /> 5. 4 true or false questions:</div>

Jakobroose