Mechanisms of Signal Transduction and Cell Regulation - Bewerkingsoverzicht

R0793161: /* Examenvragen */

2026-01-19T11:20:15Z

Examenvragen

← Oudere versie		Versie van 19 jan 2026 13:20
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	== Examenvragen ==		== Examenvragen ==
			===19 January 2026 ===
			Van den broeck: explain in detail how insulin regulates the levels of glycogen stored in the hepatocytes and he gives the figure about GSK3B and glycogen synthase

			Winderickx: 1) explain the role of Rip1 kinase in programmed cell death 2) Explain briefly how some people can have tetrachromatic color vision

			Mizuno: 1) explain common structures in protein kinases and also include catalytic site and P-loop 2) explain external activation of classical PKC 3) explain how the C2 domain plays a role in the activation of PKC

	===01 September 2025 ===		===01 September 2025 ===

R0946338: /* Examenvragen */

2026-01-16T09:05:56Z

Examenvragen

← Oudere versie		Versie van 16 jan 2026 11:05
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	===01 September 2025 ===		===01 September 2025 ===
	~~VDB~~: Question related to 'Sevenless mutations in Drosohila'		Van den Broeck: Question related to 'Sevenless mutations in Drosohila'

	JW: Bcl-2 family, function, classification based on protein domains, schematic representation of pathway in which they operate and short explanation of the other players in this pathway.		Winderickx: Bcl-2 family, function, classification based on protein domains, schematic representation of pathway in which they operate and short explanation of the other players in this pathway.

	HM: Question related to H2O2 as a signaling molecule + pathway involved		Mizuno: Question related to H2O2 as a signaling molecule + pathway involved

	===20 january 2025 ===		===20 january 2025 ===
	~~VDB~~: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors (alpha1, alpha2, beta1, beta2), which methods would you use? explain		Van den Broeck: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors (alpha1, alpha2, beta1, beta2), which methods would you use? explain

	JW: A: explain GRK, GoLoco, phosducin, RAMP, RGS briefly. B: explain role of TNFR and RIP1 in regulated cell death briefly		Winderickx: A: explain GRK, GoLoco, phosducin, RAMP, RGS briefly. B: explain role of TNFR and RIP1 in regulated cell death briefly

	HM: A: general structures in protein kinases B: external activation of classical PKC C: how does C2 domain play a role in activation		Mizuno: A: general structures in protein kinases B: external activation of classical PKC C: how does C2 domain play a role in activation

	===22 January 2024 ===		===22 January 2024 ===

R0925551: /* Examenvragen */

2025-09-12T11:56:15Z

Examenvragen

← Oudere versie		Versie van 12 sep 2025 13:56
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	== Examenvragen ==		== Examenvragen ==

			===01 September 2025 ===
			VDB: Question related to 'Sevenless mutations in Drosohila'

			JW: Bcl-2 family, function, classification based on protein domains, schematic representation of pathway in which they operate and short explanation of the other players in this pathway.

			HM: Question related to H2O2 as a signaling molecule + pathway involved

	===20 january 2025 ===		===20 january 2025 ===
	VDB: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors (alpha1, alpha2, beta1, beta2), which methods would you use? explain		VDB: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors (alpha1, alpha2, beta1, beta2), which methods would you use? explain

R0887006: /* Vakinformatie */

2025-01-26T09:34:57Z

Vakinformatie

← Oudere versie		Versie van 26 jan 2025 11:34
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	Vak uit de master B&B - cellulaire orientatie. Gedoceerd door 3 proffen: Hideaki Mizuno (vroeger Marc de Ley), Joris Winderickx en Jozef Vanden Broeck.		Vak uit de master B&B - cellulaire orientatie. Gedoceerd door 3 proffen: Hideaki Mizuno (vroeger Marc de Ley), Joris Winderickx en Jozef Vanden Broeck.
	Er vallen bonuspunten te verdienen tijdens het jaar door powerpoints te presenteren over opgelegde papers.		Er vallen bonuspunten te verdienen tijdens het jaar door powerpoints te presenteren over opgelegde papers.
	Bij één van de drie proffen moet je een paper mondeling bespreken. De andere twee hebben elk één vraag die je schriftelijk moet beantwoorden.		Bij één van de drie proffen moet je een paper mondeling bespreken. De andere twee hebben elk één vraag die je schriftelijk moet beantwoorden. (2024-2025: volledig schriftelijk, er zijn wel nog verplicht te lezen papers (2 voor Mizuno, vrij veel voor Winderickx) die aansluiten bij de leerstof, maar waar niets expliciet van is gevraagd)

	EXAMENVRAGEN KOMEN TERUG!		EXAMENVRAGEN KOMEN TERUG!

R0899163: /* 20 january 2025 */

2025-01-20T18:05:20Z

20 january 2025

← Oudere versie		Versie van 20 jan 2025 20:05
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	== Examenvragen ==		== Examenvragen ==
	===20 january 2025 ===		===20 january 2025 ===
	VDB: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors, which methods would you use? explain		VDB: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors (alpha1, alpha2, beta1, beta2), which methods would you use? explain

	JW: A: explain GRK, GoLoco, phosducin, RAMP, RGS briefly. B: explain role of TNFR and RIP1 in regulated cell death briefly		JW: A: explain GRK, GoLoco, phosducin, RAMP, RGS briefly. B: explain role of TNFR and RIP1 in regulated cell death briefly

R0899163: /* Examenvragen */

2025-01-20T17:29:50Z

Examenvragen

← Oudere versie		Versie van 20 jan 2025 19:29
Regel 10:		Regel 10:

	== Examenvragen ==		== Examenvragen ==
			===20 january 2025 ===
			VDB: picture adregenic receptors agonists and antagonists, how do you differentiate between these receptors, which methods would you use? explain

			JW: A: explain GRK, GoLoco, phosducin, RAMP, RGS briefly. B: explain role of TNFR and RIP1 in regulated cell death briefly

			HM: A: general structures in protein kinases B: external activation of classical PKC C: how does C2 domain play a role in activation

	===22 January 2024 ===		===22 January 2024 ===

R0839092 op 22 jan 2024 om 19:46

2024-01-22T19:46:29Z

← Oudere versie		Versie van 22 jan 2024 21:46
Regel 10:		Regel 10:

	== Examenvragen ==		== Examenvragen ==
			===22 January 2024 ===

			Van den Broeck:
			Give 3 examples of function-based assays for GPCR-ligand binding, and give (dis)advantages by comparing the techniques + how can you differentiate between agonists, inverse agonists and competitive antagonists?

			Winderickx:
			Bcl-2 family, function, classification based on protein domains, schematic representation of pathway in which they operate and short explanation of the other players in this pathway.

			Mizuno:
			Explain the structure of the EF-hand motif and the C2 domain. How do they interact and bind with Ca2+? Give an exemple (one of each) of molecules that contain an EF-hand motif/C2 domain and explain how they transduce signals.

	===23 January 2023 ===		===23 January 2023 ===

R0871481: /* 23 January 2023 */

2023-01-23T09:54:13Z

23 January 2023

@@ Regel 11: / Regel 11: @@
 == Examenvragen ==
 ===23 January 2023 ===
-# Mizuno: EF hand motif and C2 domain, structure, how they bind Ca2+, examples of proteins containing one of these and how they transduce signals
-# Winderickx: Explain: RAMPs, Arrestin alpha beta, GoLoco,RGS and GRKs. What is apoptosoom and necroptosoom/ribtosoom and how is it recruited?
+points for each section. An average will be taken of the three parts.
-# Vanden Broeck: a) Figure of synaps explain steps (1-5) b) What is mode of action for neurotransmitters (e.g. acetylcholine)
 ===04 February 2022 ===

R0786661: /* 23 January 2023 */

2023-01-23T09:39:33Z

23 January 2023

← Oudere versie		Versie van 23 jan 2023 11:39
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	===23 January 2023 ===		===23 January 2023 ===
	# Mizuno: EF hand motif and C2 domain, structure, how they bind Ca2+, examples of proteins containing one of these and how they transduce signals		# Mizuno: EF hand motif and C2 domain, structure, how they bind Ca2+, examples of proteins containing one of these and how they transduce signals
	# Winderickx: Arrestin alpha beta, GoLoco, GRKs~~, (nog een paar)~~. What is apoptosoom and necroptosoom/ribtosoom and how is it recruited?		# Winderickx: Explain: RAMPs, Arrestin alpha beta, GoLoco,RGS and GRKs. What is apoptosoom and necroptosoom/ribtosoom and how is it recruited?
	# Vanden Broeck: a) Figure of synaps explain steps (1-5) b) What is mode of action for neurotransmitters (e.g. acetylcholine)		# Vanden Broeck: a) Figure of synaps explain steps (1-5) b) What is mode of action for neurotransmitters (e.g. acetylcholine)

R0786661: /* 23 January 2023 */

2023-01-23T09:37:08Z

23 January 2023

← Oudere versie		Versie van 23 jan 2023 11:37
Regel 12:		Regel 12:
	===23 January 2023 ===		===23 January 2023 ===
	# Mizuno: EF hand motif and C2 domain, structure, how they bind Ca2+, examples of proteins containing one of these and how they transduce signals		# Mizuno: EF hand motif and C2 domain, structure, how they bind Ca2+, examples of proteins containing one of these and how they transduce signals
	# Winderickx: ~~Arresstin~~ alpha beta, GoLoco, GRKs, (nog een paar). What is apoptosoom and necroptosoom/ribtosoom and how is it recruited?		# Winderickx: Arrestin alpha beta, GoLoco, GRKs, (nog een paar). What is apoptosoom and necroptosoom/ribtosoom and how is it recruited?
	# Vanden Broeck: a) Figure of synaps explain steps (1-5) b) What is mode of action for neurotransmitters (e.g. acetylcholine)		# Vanden Broeck: a) Figure of synaps explain steps (1-5) b) What is mode of action for neurotransmitters (e.g. acetylcholine)