Biomolecular Modelling: verschil tussen versies
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== Examenvragen == | == Examenvragen == | ||
Exam of 21/01/2020 | |||
1. Describe the different methods for structure prediction and explain in which situation they are used. | |||
2. Differences and similarities between genetic algorithms and monte carlo simulated annealing. | |||
3. You have a set of molecules able to bind a target, but they can not be used as drugs. There is a database of drug-like compounds. You have the structure of the active ligands, of the target but not of the complex. What would you do to find new drugs? | |||
4. Random question: describe the steps of moelcular dynamics | |||
5. True or false questions: | |||
a. The PDB is the best format to store data of protein-ligand complexes | |||
b. FF for small molecules can not be used for proteins | |||
c. The first step of conjugate gradient is steepest descent | |||
Versie van 22 jan 2020 00:09
Vakinformatie
Biomolecular modelling
ECTS-fiche: https://onderwijsaanbod.kuleuven.be/syllabi/e/G0G79AE.htm
Examenvragen
Exam of 21/01/2020 1. Describe the different methods for structure prediction and explain in which situation they are used. 2. Differences and similarities between genetic algorithms and monte carlo simulated annealing. 3. You have a set of molecules able to bind a target, but they can not be used as drugs. There is a database of drug-like compounds. You have the structure of the active ligands, of the target but not of the complex. What would you do to find new drugs? 4. Random question: describe the steps of moelcular dynamics 5. True or false questions:
a. The PDB is the best format to store data of protein-ligand complexes
b. FF for small molecules can not be used for proteins
c. The first step of conjugate gradient is steepest descent