Applied Medical Biotechnology: verschil tussen versies
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| Regel 9: | Regel 9: | ||
===19 januari 2023=== | ===19 januari 2023=== | ||
Cools: | Cools: | ||
# | # a) PROTAC b) Problems when using in cancer treatment | ||
# | # ChIP-sequencing | ||
# | # ShRNA screen against 100 genes of which 1 causing drug resistance | ||
# a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis? | # a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis? | ||
Eelen: | Eelen: | ||
# | # What is meant by 'Gene transfer in somatic cells'? Give an example. - max. 5 lines | ||
# | # How can the Cre/LoxP system be made inducible? Can it be made tissue specific? - max. 5 lines | ||
# | # Explain the Tet-on/Tet-off system schematically. Can it be made tissue specific? - max. 1 page | ||
Lambrechts: | Lambrechts: | ||
# | # PRS? How did it originate? How can it be used for breast cancer? | ||
# | # Methylation as chemical marker? Chemical reaction? Use? | ||
Van Den Steen: | Van Den Steen: | ||
# | # Passive immunisation therapy against cerebral malaria | ||
# | # Difluoro-methylornithine | ||
Versie van 19 jan 2023 18:29
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Examenvragen
19 januari 2023
Cools:
- a) PROTAC b) Problems when using in cancer treatment
- ChIP-sequencing
- ShRNA screen against 100 genes of which 1 causing drug resistance
- a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis?
Eelen:
- What is meant by 'Gene transfer in somatic cells'? Give an example. - max. 5 lines
- How can the Cre/LoxP system be made inducible? Can it be made tissue specific? - max. 5 lines
- Explain the Tet-on/Tet-off system schematically. Can it be made tissue specific? - max. 1 page
Lambrechts:
- PRS? How did it originate? How can it be used for breast cancer?
- Methylation as chemical marker? Chemical reaction? Use?
Van Den Steen:
- Passive immunisation therapy against cerebral malaria
- Difluoro-methylornithine