Applied Medical Biotechnology: verschil tussen versies

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R0811248 (overleg | bijdragen)
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R0811248 (overleg | bijdragen)
Regel 9: Regel 9:
===19 januari 2023===
===19 januari 2023===
Cools:
Cools:
#
# a) PROTAC b) Problems when using in cancer treatment
#
# ChIP-sequencing
#
# ShRNA screen against 100 genes of which 1 causing drug resistance
# a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis?
# a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis?


Eelen:
Eelen:
#
# What is meant by 'Gene transfer in somatic cells'? Give an example. - max. 5 lines
#
# How can the Cre/LoxP system be made inducible? Can it be made tissue specific? - max. 5 lines
#
# Explain the Tet-on/Tet-off system schematically. Can it be made tissue specific? - max. 1 page


Lambrechts:
Lambrechts:
#
# PRS? How did it originate? How can it be used for breast cancer?
#
# Methylation as chemical marker? Chemical reaction? Use?


Van Den Steen:
Van Den Steen:
#
# Passive immunisation therapy against cerebral malaria
#
# Difluoro-methylornithine

Versie van 19 jan 2023 18:29

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Examenvragen

19 januari 2023

Cools:

  1. a) PROTAC b) Problems when using in cancer treatment
  2. ChIP-sequencing
  3. ShRNA screen against 100 genes of which 1 causing drug resistance
  4. a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis?

Eelen:

  1. What is meant by 'Gene transfer in somatic cells'? Give an example. - max. 5 lines
  2. How can the Cre/LoxP system be made inducible? Can it be made tissue specific? - max. 5 lines
  3. Explain the Tet-on/Tet-off system schematically. Can it be made tissue specific? - max. 1 page

Lambrechts:

  1. PRS? How did it originate? How can it be used for breast cancer?
  2. Methylation as chemical marker? Chemical reaction? Use?

Van Den Steen:

  1. Passive immunisation therapy against cerebral malaria
  2. Difluoro-methylornithine