Model Organisms in Biological Research

Vakinformatie

Model Organisms in biological research

ECTS-fiche: https://onderwijsaanbod.kuleuven.be/syllabi/e/G0G43AE.htm

Examenvragen

2020 January

What is a polytene chromosome and how is it used for genetics? (Extra questions: Why was it easier to have this to study genetics, answer because it is much bigger thanks to endoduplication which means that you can see it under a microscope. If you would have found a piece of the chromosome and you can sequence it, how can you find where it is located on the polytene chromosome, answer was in situ hybridisation [You can't answer CRISPR or something like that because it didn't exist back then].)

ES technology, any alternatives?

Give three tetrads

- explain the Tet system

- explain tetrad analysis

- explain transformation in Arabidopsis thaliana.

- Explain P elements

- QTL mapping

2019 January

ES technology mice

QTL mapping

Optogenetics

give examples of prokaryotes in biological research and explain their use

what are terminator seeds, what is their use and given an example of how they work

2017-2018 January

Wich primates are used as model organism and for which applications?

Explain Tetrad analysis and the application.

Explain Pronucleus injection in mice and the application.

Explain foward genetics in C. elegans.

Explain Cre recombinase system and how to use it giving examples