Applied Medical Biotechnology

Vakinformatie

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ECTS-fiche:

Examenvragen

19 januari 2023

Cools:

1. a) PROTAC b) Problems when using in cancer treatment
2. ChIP-sequencing
3. ShRNA screen against 100 genes of which 1 causing drug resistance
4. a) What is clonal hematopoiesis? b) 100 people, how do you find out who has CH? Describe step by step: what do you need/what technology do you use/how do you perform data analysis?

Eelen:

1. What is meant by 'Gene transfer in somatic cells'? Give an example. - max. 5 lines
2. How can the Cre/LoxP system be made inducible? Can it be made tissue specific? - max. 5 lines
3. Explain the Tet-on/Tet-off system schematically. Can it be made tissue specific? - max. 1 page

Lambrechts:

1. PRS? How did it originate? How can it be used for breast cancer?
2. Methylation as chemical marker? Chemical reaction? Use?

Van Den Steen:

1. Passive immunisation therapy against cerebral malaria
2. Difluoro-methylornithine