Advanced Organic Chemistry

28 januari 2013 NM

1. Explain the following reaction.
2. How is given cyclopropane synthesized from diethyl malonate in several steps? Choose reagents such that a maximal yield is obtained. Bestand:Voorbeeld.png
3. This reaction scheme is an example of a benzannelation reaction. Upon heating, several consecutive steps happen so that the given end product is obtained. Among these steps are three electrocyclic reactions (two 4-electron and one 6-electron), a tautomerization, and a cycloaddition (not necessarily in this order). Bestand:Voorbeeld.png
4. Explain formation of this product in presence of base. Bestand:Voorbeeld.png
5. Give product A and explain how this reaction occurs. Bestand:Voorbeeld.png
6. What products will be formed in following reactions? Bestand:Voorbeeld.png