Chemical Biology

Vakinformatie

Nieuw vak vanaf 2025-2026.

Examenvragen

19/06/2026

- When is it better to use TLC over LC-MS

- Ribozymes: function small vs large

- Bump hole strategy: how specifically used in ASCG, give general principle using enzyme we have seen in class

- Give general principle, advantage and limitation: antibody based labeling, fluorescent proteins, SNAP/Halo/CLIP tags, nanobodies

- IVC: principle, how to use it to link genotype and phenotype, give example

- Why is study of glucans hard compared to nucleotides and proteins

- Give 2 genetic manipulation based strategies to activate silent natural product gene clusters

- Fragment based drug discovery

- ADC: which bioconjugation strategy should you use (justify and explain principle), explain importance of site selective conjugation in ADC development