Chemical Biology

Vakinformatie

Nieuw vak vanaf 2025-2026.

1,5 ptn: When is it better to use TLC over LC-MS
1,5 ptn: Ribozymes: function small vs large
1,5 ptn: Bump hole strategy: how specifically used in ASCG, give general principle using enzyme we have seen in class
4 ptn: Give general principle, advantage and limitation: antibody based labeling, fluorescent proteins, SNAP/Halo/CLIP tags, nanobodies
2 ptn: IVC: principle, how to use it to link genotype and phenotype, give example
1,5 ptn: Why is study of glycans hard compared to nucleotides and proteins
1,5 ptn: Give 2 genetic manipulation based strategies to activate silent natural product gene clusters
1,5 ptn: Fragment based drug discovery
3,5 ptn: ADC: which bioconjugation strategy should you use (justify and explain principle), explain importance of site selective conjugation in ADC development