Chemical Biology

Vakinformatie

Nieuw vak vanaf 2025-2026.

Examenvragen

19/06/2026

- 1,5 ptn: When is it better to use TLC over LC-MS

- 1,5 ptn: Ribozymes: function small vs large

- 1,5 ptn: Bump hole strategy: how specifically used in ASCG, give general principle using enzyme we have seen in class

- 4 ptn: Give general principle, advantage and limitation: antibody based labeling, fluorescent proteins, SNAP/Halo/CLIP tags, nanobodies

- 2 ptn: IVC: principle, how to use it to link genotype and phenotype, give example

- 1,5 ptn: Why is study of glucans hard compared to nucleotides and proteins

- 1,5 ptn: Give 2 genetic manipulation based strategies to activate silent natural product gene clusters

- 1,5 ptn: Fragment based drug discovery

- 3,5 ptn: ADC: which bioconjugation strategy should you use (justify and explain principle), explain importance of site selective conjugation in ADC development